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TSU-68 (Orantinib, SU6668)
TSU-68 (Orantinib, SU6668)
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  • 商品货号:A10953
  • 名称:TSU-68 (Orantinib, SU6668)
  • 简介:Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. Phase 3.
  • CASNO:252916-29-3
  • 分子式:C18H18N2O3
  • 分子量:310.4
  • SMILES:CC1=C(NC(=C1CCC(=O)O)C)/C=C2/C3=CC=CC=C3NC2=O
  • 保持条件:at -20°C 3 years Powder
  • 同名:TSU68
  • 纯度:>98%
  • 应用:PDFGRβ inhibitor
  • 作用机制:Inhibitor