- 商品货号:A12615
- 名称:GSK481
- 简介:GSK481 is a novel benzoxazepinone (BOAz) series of RIP1 inhibitors. Receptor Interacting Protein Kinase 1 (RIP1) has been implicated as a key contributor to inflammation through the regulation of programmed necrosis. Inhibition of this kinase has been shown to hinder cell necrotic death, thereby establishing RIP1 as a viable target for the potential treatment of multiple inflammatory diseases.
- CASNO:1622849-58-4
- 分子式:C21H19N3O4
- 分子量:377.39
- SMILES:O=C(C1=NOC(CC2=CC=CC=C2)=C1)N[C@H]3COC4=CC=CC=C4N(C)C3=O
- 保持条件:at -20°C 3 years Powder
- 同名:GSK 481, GSK-481
- 纯度:>98%
- 应用:RIP1 inhibitor
- 作用机制:Inhibitor