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GSK-J4
GSK-J4
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  • 商品货号:A12732
  • 名称:GSK-J4
  • 简介:GSK J4 is a cell permeable prodrug rapidly hydrolyzed by macrophage esterases to GSK-J1, a potent selective jumonji H3K27 demethylase inhibitor; attenuates lipopolysaccharide (LPS)-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 uM for the inhibition of TNF?? release).
  • CASNO:1373423-53-0
  • 分子式:C24H27N5O2
  • 分子量:417.5
  • SMILES:CCOC(=O)CCNC1=NC(=NC(=C1)N2CCC3=CC=CC=C3CC2)C4=CC=CC=N4
  • 保持条件:at -20°C 3 years Powder
  • 同名:GSK J4
  • 纯度:>98%
  • 应用:Demethylase Inhibitor
  • 作用机制:Inhibitor