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RI-1
RI-1
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  • 商品货号:A13187
  • 名称:RI-1
  • 简介:RI-1 is a small molecule that inhibits the central recombination protein RAD51. RI-1 specifically reduces gene conversion in human cells while stimulating single strand annealing. RI-1 binds covalently to the surface of RAD51 protein at cysteine 319 that likely destabilizes an interface used by RAD51 monomers to oligomerize into filaments on DNA.
  • CASNO:415713-60-9
  • 分子式:C14H11Cl3N2O3
  • 分子量:361.61
  • SMILES:C1COCCN1C2=C(C(=O)N(C2=O)C3=CC(=C(C=C3)Cl)Cl)Cl
  • 保持条件:at -20°C 3 years Powder
  • 同名:RI1?? RI 1
  • 纯度:>98%
  • 应用:RAD51 Inhibitor II
  • 作用机制:Inhibitor