- 商品货号:A13187
- 名称:RI-1
- 简介:RI-1 is a small molecule that inhibits the central recombination protein RAD51. RI-1 specifically reduces gene conversion in human cells while stimulating single strand annealing. RI-1 binds covalently to the surface of RAD51 protein at cysteine 319 that likely destabilizes an interface used by RAD51 monomers to oligomerize into filaments on DNA.
- CASNO:415713-60-9
- 分子式:C14H11Cl3N2O3
- 分子量:361.61
- SMILES:C1COCCN1C2=C(C(=O)N(C2=O)C3=CC(=C(C=C3)Cl)Cl)Cl
- 保持条件:at -20°C 3 years Powder
- 同名:RI1?? RI 1
- 纯度:>98%
- 应用:RAD51 Inhibitor II
- 作用机制:Inhibitor