• accession：NM_014772
• 基因别名：Gm672; KIAA0427
• 基因描述：Homo sapiens CBP80/20-dependent translation initiation factor (CTIF), transcript variant 1, mRNA.
• 载体：现货载体
• CDS区长度：1797
• 翻译后氨基酸长度：598
• TranscriptVariant：This variant (1) represents the more predominant transcript and encodes isoform 1.
• 基因简介：CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 [PubMed 19648179]).[supplied by OMIM, Dec 2009]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGAAAACTCCTCTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGAGGAGC
TGGAGCGCTTCATCGACAGCTACGTGCTGGAGTACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGG
TGATGGCGAGAGCGAGAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACTGCAGCGAACCGCTGGAC
AGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCCACAGCAGAATGGCAGCAAAGACAACTCTCTGGACA
TGCTGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCACCTGGGACCTGCAGCC
GGAAAAGCTGGACTTCACCCAGTTCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATC
GACCGCGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATGGCATCAACCTGAATGACATCGAGAAGG
TCCTTCCAGCCTGGCAGGGCTACCACCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGAAGCTGTT
CCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGGGGGCAACAAGCCCCAACAGCATGGT
GACCACCAGCCAGGCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGCACCCC
ACCCCTCAGGGAGGCCCACTCACCATGGCTACAGCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCA
CCCACCAGGCGACAAGGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCATGACCATCGAGAACCCA
AAACTGGAGGACACTGCAGGGGACACCGGGCACAGCAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGG
CCCCGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGAGACAAAACGTAAAGA
CAGTATTCTTCCCGAGCGCATCGGGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTG
CGGCGAAGGCTAAAGGAAAAGGATGAAGTGGCCGTGGAGACGACCACTCCCCAGCAGAACAAGATGGACA
AGCTGATCGAGATCCTGAACAGCATGCGGAACAACAGCAGCGACGTGGACACCAAGCTCACCACCTTCAT
GGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGAGATCGTGCGCACAATCTACCAGAAG
GCTGTGTCCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTATGGTGG
AGGGGACCAAGTTCCGGAGCCTGCTCCTCAACATGCTGCAGAAGGACTTCACGGTGCGCGAGGAGCTGCA
GCAGCAGGACGTGGAGCGCTGGCTGGGCTTCATCACCTTCCTGTGCGAGGTCTTCGGCACCATGCGCAGC
AGCACAGGCGAGCCCTTCCGTGTGCTCGTGTGCCCCATCTACACCTGCCTCAGGGAGCTCTTGCAATCTC
AGGATGTGAAGGAAGATGCTGTCCTTTGCTGCTCTATGGAGCTGCAGAGTACAGGCCGGCTGCTGGAGGA
ACAGCTGCCTGAGATGATGACAGAGCTCCTGGCCAGCGCACGGGACAAGATGCTGTGCCCCTCGGAGTCC
ATGCTGACCCGGTCGCTGCTCCTAGAGGTCATCGAGCTCCACGCTAACAGCTGGAACCCTCTGACGCCCC
CCATCACGCAGTACTACAACAGAACCATCCAGAAACTGACAGCCTGA

翻译后氨基酸参数序列： 点击查看序列

ATGGAAAACTCCTCTGCAGCATCAGCCTCCTCGGAGGCAGGGAGCAGCCGCTCCCAGGAGATCGAGGAGC
TGGAGCGCTTCATCGACAGCTACGTGCTGGAGTACCAGGTGCAGGGGCTGCTGGCTGACAAGACGGAGGG
TGATGGCGAGAGCGAGAGGACCCAGTCCCACATCTCCCAGTGGACAGCGGACTGCAGCGAACCGCTGGAC
AGCAGCTGTTCCTTCTCCCGAGGGCGAGCCCCCCCACAGCAGAATGGCAGCAAAGACAACTCTCTGGACA
TGCTGGGCACGGACATCTGGGCGGCCAACACCTTCGATTCCTTCAGTGGTGCCACCTGGGACCTGCAGCC
GGAAAAGCTGGACTTCACCCAGTTCCACCGCAAAGTCCGACACACGCCCAAGCAGCCCCTGCCACACATC
GACCGCGAAGGGTGTGGCAAAGGGAAGCTGGAAGATGGGGATGGCATCAACCTGAATGACATCGAGAAGG
TCCTTCCAGCCTGGCAGGGCTACCACCCGATGCCCCATGAAGTGGAGATCGCACACACCAAGAAGCTGTT
CCGCAGGAGGAGAAATGATCGAAGGCGGCAGCAGAGACCTCCGGGGGGCAACAAGCCCCAACAGCATGGT
GACCACCAGCCAGGCAGTGCCAAACACAACAGGGACCACCAGAAATCCTACCAGGGGGGCTCAGCACCCC
ACCCCTCAGGGAGGCCCACTCACCATGGCTACAGCCAGAACCGGCGCTGGCACCATGGCAACATGAAGCA
CCCACCAGGCGACAAGGGGGAGGCAGGCGCACACCGCAATGCCAAAGAGACCATGACCATCGAGAACCCA
AAACTGGAGGACACTGCAGGGGACACCGGGCACAGCAGCCTTGAGGCCCCCCGCAGCCCTGACACCCTGG
CCCCGGTGGCTTCTGAGCGGCTGCCCCCACAGCAGTCAGGGGGGCCAGAGGTTGAGACAAAACGTAAAGA
CAGTATTCTTCCCGAGCGCATCGGGGAGCGGCCCAAAATTACCCTGCTCCAGTCTTCCAAAGACAGACTG
CGGCGAAGGCTAAAGGAAAAGGATGAAGTGGCCGTGGAGACGACCACTCCCCAGCAGAACAAGATGGACA
AGCTGATCGAGATCCTGAACAGCATGCGGAACAACAGCAGCGACGTGGACACCAAGCTCACCACCTTCAT
GGAGGAGGCCCAGAACTCCACCAACTCCGAGGAGATGCTGGGCGAGATCGTGCGCACAATCTACCAGAAG
GCTGTGTCCGACCGCAGCTTCGCCTTCACCGCTGCCAAGCTCTGCGACAAGATGGCGCTCTTTATGGTGG
AGGGGACCAAGTTCCGGAGCCTGCTCCTCAACATGCTGCAGAAGGACTTCACGGTGCGCGAGGAGCTGCA
GCAGCAGGACGTGGAGCGCTGGCTGGGCTTCATCACCTTCCTGTGCGAGGTCTTCGGCACCATGCGCAGC
AGCACAGGCGAGCCCTTCCGTGTGCTCGTGTGCCCCATCTACACCTGCCTCAGGGAGCTCTTGCAATCTC
AGGATGTGAAGGAAGATGCTGTCCTTTGCTGCTCTATGGAGCTGCAGAGTACAGGCCGGCTGCTGGAGGA
ACAGCTGCCTGAGATGATGACAGAGCTCCTGGCCAGCGCACGGGACAAGATGCTGTGCCCCTCGGAGTCC
ATGCTGACCCGGTCGCTGCTCCTAGAGGTCATCGAGCTCCACGCTAACAGCTGGAACCCTCTGACGCCCC
CCATCACGCAGTACTACAACAGAACCATCCAGAAACTGACAGCCTGA