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- accession：NM_022804
- 基因描述：Homo sapiens SNRPN upstream reading frame (SNURF), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：216
- 翻译后氨基酸长度：71
- TranscriptVariant：This variant (2) includes exons 1-3 and alternative exon 3b. Exon 3b has a polyA signal and site and its inclusion results in a truncated, monocistronic transcript. Variant 2 is the minor transcript but the monocistronic and bicistronic transcripts encode identical proteins, with alternate splicing occurring only in the 3' UTR.
- 基因简介：This gene encodes a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
