• 靶点-Target： Sp1
• MW(Observed)： 90kD
• 宿主物种-Host Species： Rabbit
• 同种型-Isotype： IgG
• 修饰-Modification： Acetyl
• 推荐稀释比： WB 1:500-2000;IHC 1:50-300
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 浓度： 1 mg/ml
• 克隆性： Polyclonal
• 免疫原： Synthesized peptide derived from human Sp1 (Acetyl Lys703)
• 特异性： This antibody detects endogenous levels of Human，Mouse，Rat Sp1 (Acetyl Lys703)
• 基因名称： SP1 TSFP1
• 蛋白名称： Sp1 (Acetyl Lys703)
• Organism-1： Human
• 基因ID-1： 6667
• SwissProt-1： P08047
• Organism-2： Mouse
• 基因ID-2： 20683
• SwissProt-2： O89090
• Organism-3： Rat
• 基因ID-3： 24790
• SwissProt-3： Q01714
• 背景： function:Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.，PTM:O-glycosylated; contains N-acetylglucosamine side chains.，similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.，similarity:Contains 3 C2H2-type zinc fingers.，subunit:Interacts with ATF7IP， ATF7IP2， POGZ， HCFC1， AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the two proteins in DNA binding.，
• 细胞定位： Nucleus. Cytoplasm. Nuclear location is governed by glycosylated/phosphorylated states. Insulin promotes nuclear location， while glucagon favors cytoplasmic location.

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