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NCoA-3 (Acetyl Lys616) rabbit pAb
NCoA-3 (Acetyl Lys616) rabbit pAb
  • 商品货号:FAB2600419
  • WB IHC IF ELISA ICC IP FC
    活动价: ¥680元
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    • 靶点-Target: NCoA-3
    • MW(Observed): 160kD
    • 宿主物种-Host Species: Rabbit
    • 同种型-Isotype: IgG
    • 修饰-Modification: Acetyl
    • 推荐稀释比: WB 1:1000-2000;ELISA 1:5000-20000
    • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
    • 浓度: 1 mg/ml
    • 克隆性: Polyclonal
    • 免疫原: Synthesized peptide derived from human NCoA-3 (Acetyl Lys616)
    • 特异性: This antibody detects endogenous levels of Human NCoA-3 (Acetyl Lys616)
    • 基因名称: NCOA3 AIB1 BHLHE42 RAC3 TRAM1
    • 蛋白名称: NCoA-3 (Acetyl Lys616)
    • Organism-1: Human
    • 基因ID-1: 8202
    • SwissProt-1: Q9Y6Q9
    • Organism-2: Mouse
    • SwissProt-2: O09000
    • Organism-3: Rat
    • SwissProt-3: Q9EPU2
    • 背景: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010],
    • 细胞定位: Cytoplasm. Nucleus. Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsequent phosphorylation, it translocates from the cytoplasm to the nucleus.
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