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- 靶点-Target: RAB4A
- MW(Observed): 24kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant human RAB4A protein fragments expressed in E.coli.
- 特异性: This antibody detects endogenous levels of RAB4A and does not cross-react with related proteins.
- 基因名称: rab4a-n
- Organism-1: Human
- 基因ID-1: 5867
- SwissProt-1: P20338
- Organism-2: Mouse
- SwissProt-2: P56371
- 背景: This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012],
- 细胞定位: Membrane; Peripheral membrane protein . Cytoplasm . Early endosome membrane ; Peripheral membrane protein . Recycling endosome membrane ; Peripheral membrane protein . Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1. .