资料下载
- 靶点-Target: AKR1B1
- MW(Observed): 36kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:1000
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant human AKR1B1 protein fragments expressed in E.coli.
- 特异性: This antibody detects endogenous levels of AKR1B1 and does not cross-react with related proteins.
- 基因名称: akr1b1
- Organism-1: Human
- 基因ID-1: 24192
- SwissProt-1: P15121
- Organism-2: Mouse
- SwissProt-2: P45376
- 背景: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009],
- 细胞定位: Cytoplasm.