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- accession：NM_001017367
- 基因别名：C4BPB
- 基因描述：Homo sapiens complement component 4 binding protein, beta (C4BPB), transcript variant 5, mRNA.
- 载体：现货载体
- CDS区长度：759
- 翻译后氨基酸长度：252
- TranscriptVariant：This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1, 3 and 5 encode the same isoform (1).
- 基因简介：This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
