- accession:NM_001190442
- 基因别名:CAST
- 基因描述:Homo sapiens calpastatin (CAST), transcript variant 11, mRNA.
- 载体:现货载体
- CDS区长度:2088
- 翻译后氨基酸长度:695
- TranscriptVariant:This variant (11) has multiple differences in the coding region but maintains the reading frame, compared to variant 6. This variant encodes isoform m, which is shorter than isoform f.
- 基因简介:The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
- 规格:10ul 质粒
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