- accession:NM_001178130
- 基因别名:EGF
- 基因描述:Homo sapiens epidermal growth factor (EGF), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:3501
- 翻译后氨基酸长度:1166
- TranscriptVariant:This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- 基因简介:This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- 规格:10ul 质粒
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