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- 商品货号：G124661
- accession：NM_175940
- 基因别名：DUOX1
- 基因描述：Homo sapiens dual oxidase 1 (DUOX1), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：4656
- 翻译后氨基酸长度：1551
- TranscriptVariant：This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform.
- 基因简介：The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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