- accession:NM_001267040
- 基因别名:JARID2
- 基因描述:Homo sapiens jumonji, AT rich interactive domain 2 (JARID2), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:3225
- 翻译后氨基酸长度:1074
- TranscriptVariant:This variant (2) differs in the 5' UTR and initiates translation at a downstream AUG, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1.
- 基因简介:This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
- 规格:10ul 质粒
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