- accession:NM_002253
- 基因别名:KDR
- 基因描述:Homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR), mRNA.
- 载体:现货载体
- CDS区长度:4071
- 翻译后氨基酸长度:1356
- 基因简介:Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- 规格:10ul 质粒
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