- accession:NM_001282661
- 基因别名:MKL1
- 基因描述:Homo sapiens megakaryoblastic leukemia (translocation) 1 (MKL1), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:2646
- 翻译后氨基酸长度:881
- TranscriptVariant:This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1.
- 基因简介:The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
- 规格:10ul 质粒
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