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- accession：NM_001282662
- 基因别名：MKL1
- 基因描述：Homo sapiens megakaryoblastic leukemia (translocation) 1 (MKL1), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：2397
- 翻译后氨基酸长度：798
- TranscriptVariant：This variant (4) uses an alternate splice site in the 3' coding region, which results in a frameshift and an early stop codon, compared to variant 1. It encodes isoform 3, which has a shorter and distinct C-terminus, compared to isoform 1.
- 基因简介：The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
