- accession:NM_001042523
- 基因别名:Txnrd1
- 基因描述:Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1842
- 翻译后氨基酸长度:613
- TranscriptVariant:This variant (1) encodes the longer isoform (1).
- 基因简介:This gene encodes a member of the family of pyridine nucleotide-disulfide oxidoreductases. This protein is a flavoenzyme, which uses NADPH for reduction of thioredoxins as well as other protein and nonprotein substrates, and plays a role in protection against oxidative stress. It contains a selenocysteine (Sec) residue, which is essential for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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