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- accession：NM_015762
- 基因别名：Txnrd1
- 基因描述：Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：1500
- 翻译后氨基酸长度：499
- TranscriptVariant：This variant (3) has a different 5' non-coding exon, and is missing an alternate 5' coding exon compared to transcript variant 1. This results in a shorter isoform (2) with a different N-terminus compared to isoform 1. Transcript variants 2, 3 and 4 encode the same isoform.
- 基因简介：This gene encodes a member of the family of pyridine nucleotide-disulfide oxidoreductases. This protein is a flavoenzyme, which uses NADPH for reduction of thioredoxins as well as other protein and nonprotein substrates, and plays a role in protection against oxidative stress. It contains a selenocysteine (Sec) residue, which is essential for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
