细胞信息
发货规格	1×10⁶
别名	Ht-1080; HT 1080; HT1080; HT 1080.T
形态	上皮细胞样
生长特性	贴壁
培养条件	DMEM+10%FBS+1%P/S
冻存条件	90%FBS+10%DMSO
传代方式	胰酶消化
传代比例	1:2~1:4
换液频率	每周2~3次
细胞背景
种属	人源
肿瘤类型	纤维肉瘤
供体信息	35岁白人女性
背景描述	HT-1080细胞来源于1972年一名35岁男性纤维肉瘤患者的结缔组织，由于其高度侵袭性和侵袭性，被广泛用于研究肿瘤侵袭性和转移的机制。
遗传背景
同工酶	G6PD， B
基因表达	ras+
致瘤性	Yes， in immunosuppressed mice
病毒	Human poliovirus 1 Feline leukemia virus Vesicular stomatitis virus
核型	modal number = 46; range = 44 to 48.Pseudodiploidy was frequently noted. About 40% of the cells had rearranged karyotypes with an extra E-group chromosome and a group C chromosome， probably chromosome 11， was missing. Note: Cytogenetic information is based on initial seed stock at ATCC. Cytogenetic instability has been reported in the literature for some cell lines.

STR鉴定

STR位点信息

STR鉴定图

Amelogenin	X,Y
CSF1PO	11 (PubMed=17254797) 12 (ATCC=CCL-121; CCRID; CLS=300216; Cosmic-CLP=907064; DSMZ=ACC-315; ECACC=85111505; JCRB=IFO50354; JCRB=JCRB9113; KCLB=10121; PubMed=25877200; RCB=RCB1956)
D2S1338	25,26
D3S1358	16
D5S818	11,13
D7S820	9,10
D8S1179	13,14
D13S317	12,14
D16S539	9,12
D18S51	12,18
D19S433	13.2,15 (CCRID) 14,15 (DSMZ=ACC-315)
D21S11	28,30
FGA	22,25
Penta D	9,12
Penta E	5,15
TH01	6
TPOX	8
vWA	14,19