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MG-63细胞(人成骨肉瘤细胞)
MG-63细胞(人成骨肉瘤细胞)
  • 商品货号:CL0217
  • 活动价: ¥899元
    市场价:¥1800元
    已售 26 件 | 评价 0 人次 | 关注度 1757
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    • 细胞信息
     
    发货规格 1×10⁶
    别名 M-G63;MG63
    形态 成纤维细胞样
    生长特性 贴壁
    培养条件 MEM+10%FBS+1%P/S
    冻存条件 90%FBS+10%DMSO
    传代方式 胰酶消化
    倍增时间 38~48h
    传代比例 1:2~1:4
    换液频率 每周2~3次
    生物安全等级 1
    • 细胞背景
     
    种属 人源
    组织来源
    肿瘤类型 骨肉瘤
    供体信息 14岁白人男性
    背景描述 MG-63细胞是一种源自14岁白人男性骨肉瘤患者骨骼的人类骨肉瘤细胞系,是骨生物学研究的关键模型。MG63人骨肉瘤细胞具有成纤维细胞形态和快速增殖,是了解骨代谢的重要工具,特别是在骨肉瘤的背景下。当用聚肌苷酸-多胞苷酸、环己酰亚胺和放线菌素D等药物诱导时,MG-63细胞会产生高水平的人干扰素。
    • 遗传背景
     
    受体表达 Transforming growth factor beta (TGF beta, type I and type II),
    基因表达 Interferon
    核型 This is a hypotriploid human cell line. The modal chromosome number was 66 occurring in 44% of cells. The rate of cells with higher ploidies was 2.0%. Eighteen to 19 marker chromosomes were common to all cells.
    STR鉴定
    STR位点信息
    STR鉴定图
    Amelogenin X,Y
    CSF1PO 10,12
    D2S1338 17,24
    D3S1358 15
    D5S818 11,12
    D7S820 10
    D8S1179 13
    D13S317 11
    D16S5391978779225877200 11 (AddexBio=C0004007/4991; ATCC=CRL-1427; CCRID; Cosmic-CLP=908131; ECACC=86051601; PubMed=19787792; PubMed=25877200; RCB=RCB1890; TKG=TKG 0294) 11,12 (CLS=300441; JCRB=IFO50108)
    D18S51 16
    D19S433 13,14
    D21S11 30
    FGA 21,25
    Penta D 9,13
    Penta E 11,12
    SE33 20
    TH01 9.3
    TPOX 8,11
    vWA 16,19

    参考文献

    Preparation of thiolated poly (lactic acid) microspheres by amine ester reaction to simulate three-dimensional inkjet printing (3DP) biocompatible scaffolds(2024-05-15)
    IF: 13.20
    作者:Haotian Ma ,Yuelei Wang ,Guanhang Qu ,Xiaoming Guo ,Ni Jiang ,Lifen Zhao
    单位:School of Materials Science and Engineering, Shandong University of Science and Technology, Qingdao 266590, China
    期刊: Chemical Engineering Journal
    DOI: 10.1016/j.cej.2024.151075
    Distinct degradation behaviors of semi-crystalline poly (4-hydroxybutyrate) containing a nucleating agent under enzymatic or alkaline conditions(2022-09-01)
    IF: 7.40
    作者:Xinyu Mu,Lin Yang,Yong Shen,Zhenbo Ning,Ni Jiang,Zhibo Li,Zhihua Gan
    单位:State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomaterials, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China
    期刊: Polymer Degradation and Stability
    DOI: 10.1016/j.polymdegradstab.2022.110081
    Evading stability-biocompatibility tradeoff in TiNb coatings with armour-like super hydrophilic micro-nano structure surface(2023-10-01)
    IF: 6.60
    作者:Yu Zheng,Peng Xu,Long Li,Qibin Liu
    单位:College of Materials and Metallurgy, Guizhou University, Guiyang, 550025, China
    期刊: Journal of Materials Research and Technology
    DOI: 10.1016/j.jmrt.2023.08.084