• 名称：Danusertib (PHA-739358)
• 简介：Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc. Phase 2
• CASNO：827318-97-8
• 分子式：C26H30N6O3
• 分子量：474.6
• SMILES：CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3CN(C4)C(=O)[C@@H](C5=CC=CC=C5)OC
• 保持条件：at -20°C 3 years Powder
• 同名：PHA739358
• 纯度：>98%
• 应用：Aurora inhibitor
• 作用机制：Inhibitor