• 名称：Pexmetinib (ARRY-614)
• 简介：Pexmetinib is a potent inhibitor of cytokine synthesis, via the dual inhibition of p38 mitogen-activated protein kinase (MAPK), and Tie2/Tek receptor tyrosine kinase.
• CASNO：945614-12-0
• 分子式：C31H33FN6O3
• 分子量：556.63
• SMILES：O=C(NCC1=CC(F)=CC=C1OC2=CC3=C(N(CCO)N=C3)C=C2)NC4=CC(C(C)(C)C)=NN4C5=CC=C(C)C=C5
• 保持条件：at -20°C 3 years Powder
• 同名：ARRY614, ARRY 614
• 纯度：>98%
• 应用：p38 MAPK inhibitor
• 作用机制：Inhibitor