- 名称:AMG 548
- 简介:AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blood LPS-stimulated TNFα.
- CASNO:864249-60-5
- 分子式:C29H27N5O
- 分子量:461.56
- SMILES:O=C1N(C)C(NC[C@H](CC2=CC=CC=C2)N)=NC(C3=CC=NC=C3)=C1C4=CC=C5C(C=CC=C5)=C4
- 保持条件:at -20°C 3 years Powder
- 同名:AMG-548, AMG548
- 纯度:>98%
- 应用:p38 MAPK inhibitor
- 作用机制:Inhibitor