- 名称:XL647 (Tesevatinib)
- 简介:XL647 is an orally bioavailable small-molecule RTK inhibitor that binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization, including EGFR, HER2, ERBB2, VEGFR and EphB4.
- CASNO:874286-84-7
- 分子式:C24H25Cl2FN4O2
- 分子量:491.4
- SMILES:CN1CCCC(CCC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=CC(=C(C(=C4)Cl)Cl)F)OC
- 保持条件:at -20°C 3 years Powder
- 同名:XL 647, XL-647, EXEL-7647
- 纯度:>98%
- 应用:EGFR, HER2 and VEGFR inhibitor
- 作用机制:Inhibitor