- 名称:PF-03814735
- 简介:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.
- CASNO:942487-16-3
- 分子式:C23H25F3N6O2
- 分子量:474.48
- SMILES:CC(=O)NCC(=O)N1[C@H]2CC[C@@H]1C3=C2C=CC(=C3)NC4=NC=C(C(=N4)NC5CCC5)C(F)(F)F
- 保持条件:at -20°C 3 years Powder
- 同名:PF03814735
- 纯度:>98%
- 应用:Aurora A/B Kinase inhibitor
- 作用机制:Inhibitor