- 名称:Refametinib
- 简介:Refametinib is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.
- CASNO:923032-37-5
- 分子式:C19H20F3IN2O5S
- 分子量:572.34
- SMILES:COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)C[C@@H](CO)O)NC3=C(C=C(C=C3)I)F)F)F
- 保持条件:at -20°C 3 years Powder
- 同名:BAY 869766,RDEA119, Bay 86-9766
- 纯度:>98%
- 应用:MEK inhibitor
- 作用机制:Inhibitor