• 名称：KPT185
• 简介：KPT185 is a selective CRM1 inhibitor. KPT-185 significantly inhibits leukemia cell proliferation with IC50 ranging from 100 nM to 500 nM, and induces cell-cycle arrest and apoptosis of AML cell lines and primary AML blasts.
• CASNO：1333151-73-7
• 分子式：C16H16F3N3O3
• 分子量：355.31
• SMILES：CC(C)OC(=O)C=CN1C=NC(=N1)C2=CC(=CC(=C2)OC)C(F)(F)F
• 保持条件：at -20°C 3 years Powder
• 同名：KPT 185, KPT-185
• 纯度：>98%
• 应用：CRM1 Inhibitor
• 作用机制：Inhibitor