• 名称：XL-228
• 简介：XL228 is a protein kinase inhibitor targeting IGF1R, the AURORA kinases, FGFR1-3, ABL and SRC family kinases. XL228 is an Aurora A inhibitor (IC50, f3 nmol/L) that has shown potent biochemical activity against ABL1 (Ki, 5 nmol/L), as well as the BCR-ABL1 T315I (Ki, 1.4 nmol/L) kinases.
• CASNO：898280-07-4
• 分子式：C28H37N9O
• 分子量：515.65
• SMILES：CC(C)C1=NOC(=C1)CNC2=NC(=CC(=N2)NC3=NNC(=C3)C4CC4)N5CCN(CC5)C
• 保持条件：at -20°C 3 years Powder
• 纯度：>98%
• 应用：IGF-1R, Aurora, FGFR, ABL, SRC inhibitor
• 作用机制：Inhibitor