- 名称:R1530
- 简介:R1530 is a pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. R1530 is also a mitosis-angiogenesis inhibitor (MAI) that inhibits multiple receptor tyrosine kinases involved in angiogenesis, such as vascular endothelial growth factor receptor (VEGFR)-1, -2, -3, platelet-derived growth factor receptor (PDGFR) beta? FMS-like tyrosine kinase (Flt)-3, and fibroblast growth factor receptor (FGFR) -1, -2.
- CASNO:882531-87-5
- 分子式:C18H14ClFN4O
- 分子量:356.78
- SMILES:CC1=C2C(=NC3=CC(=C(C=C3C(=N2)C4=CC=CC=C4Cl)F)OC)NN1
- 保持条件:at -20°C 3 years Powder
- 同名:R-1530, R 1530
- 纯度:>98%
- 应用:Chk2, KDR, FGFR, Aurora A & Cdk2 inhibitor
- 作用机制:Inhibitor