- 名称:NSC348884
- 简介:NSC348884 is a nucleolar phosphoprotein that displays several biological activities in ribosome biogenesis, cell proliferation, cytoplasmic/nuclear shuttle transportation, nucleic acid binding, ribonucleic cleavage, and centrosome duplication. NSC 348884 is a putative inhibitor of nucleophosmin (NPM). NSC 348884 inhibits NMP oligomer formation, up-regulates p53 and induces apoptosis.
- CASNO:81624-55-7
- 分子式:C38H40N10
- 分子量:636.79
- SMILES:CC1=CC2=C(C=C1)N=C(N2)CN(CCN(CC3=NC4=C(N3)C=C(C=C4)C)CC5=NC6=C(N5)C=C(C=C6)C)CC7=NC8=C(N7)C=C(C=C8)C
- 保持条件:at -20°C 3 years Powder
- 同名:NSC 348884, NSC-348884
- 纯度:>98%
- 应用:nucleophosmin inhibitor
- 作用机制:Inhibitor