- 名称:NSC59984
- 简介:NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 uM for p53-null HCT116 cells.
- CASNO:803647-40-7
- 分子式:C12H15N3O4
- 分子量:265.27
- SMILES:CN1CCN(CC1)C(=O)C=CC2=CC=C(O2)[N+](=O)[O-]
- 保持条件:at -20°C 3 years Powder
- 同名:NSC 59984, NSC-59984
- 纯度:>98%
- 应用:P53 Activator
- 作用机制:Activator