- 名称:AMG-47a
- 简介:AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.
- CASNO:882663-88-9
- 分子式:C29H28F3N5O2
- 分子量:535.56
- SMILES:CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=CN=C(N=C4C=C3)NCCN5CCOCC5
- 保持条件:at -20°C 3 years Powder
- 同名:AMG47a, Geneticin
- 纯度:>98%
- 应用:Lck inhibitor
- 作用机制:Inhibitor