• 名称：GF 109203X
• 简介：GF 109203X is a potent and selective inhibitor of protein kinase C, selective for the α and β1 isoforms (IC50 values are 0.0084, 0.0180, 0.210, 0.132, and 5.8 μM for α, β1, δ, ε and ζ isoforms respectively). Selective over MLCK, PKG and PKA (IC50 values are 0.6, 4.6, and 33 μM respectively). Potent antagonist at the 5-HT3 receptor (Ki = 29.5 nM).
• CASNO：133052-90-1
• 分子式：C25H24N4O2
• 分子量：412.49
• SMILES：CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
• 保持条件：at -20°C 3 years Powder
• 同名：GF-109203X, GF109203X, GO6850, GO-6850, Bisindolylmaleimide I
• 纯度：>98%
• 应用：PKC inhibitor
• 作用机制：Inhibitor