- 名称:Ro 31-8220
- 简介:Ro 31-8220 is a PKC-inhibitor, which inhibits stimulated fluid pinocytosis of human PMNs induced by the PKC-activators phorbol myristate acetate (PMA, IC50 = 1.35 x 10(-6) M) or diacylglycerols (OAG, diC8) by 95%.
- CASNO:138489-18-6
- 分子式:C25H23N5O2SCH3SO3H
- 分子量:553.7
- SMILES:CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCSC(=N)N.CS(=O)(=O)O
- 保持条件:at -20°C 3 years Powder
- 同名:BIM IX, Bisindolylmaleimide IX (mesylate)
- 纯度:>98%
- 应用:PKC inhibitor
- 作用机制:Inhibitor