• 名称：CC-930 (Tanzisertib)
• 简介：CC-930 is kinetically competitive with ATP in the JNK-dependent phosphorylation of the protein substrate c-Jun and potent against all isoforms of JNK (Ki(JNK1) = 44 ± 3 nM, IC50(JNK1) = 61 nM, Ki(JNK2) = 6.2 ± 0.6 nM, IC50(JNK2) = 5 nM, IC50(JNK3) = 5 nM) and selective against MAP kinases ERK1 and p38a with IC50 of 0.48 and 3.4 μM respectively
• CASNO：899805-25-5
• 分子式：C21H23F3N6O2
• 分子量：448.44
• SMILES：C1COC[C@H]1N2C3=NC(=NC=C3N=C2NC4=C(C=C(C=C4F)F)F)NC5CCC(CC5)O
• 保持条件：at -20°C 3 years Powder
• 同名：Tanzisertib, CC 930, CC930
• 纯度：>98%
• 应用：JNK inhibitor
• 作用机制：Inhibitor