- 名称:Sivelestat sodium salt
- 简介:Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.
- CASNO:150374-95-1
- 分子式:C20H21N2NaO7S
- 分子量:456.44
- SMILES:CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]
- 保持条件:at -20°C 3 years Powder
- 同名:ONO-5046
- 纯度:>98%
- 应用:Neutrophil elastase inhibitor
- 作用机制:Inhibitor