• 名称：Dabrafenib Mesylate
• 简介：Dabrafenib Mesylate is a novel, potent, and selective Raf kinase inhibitor that is capableof inhibiting the kinase activity of wild-type B-Raf, B-RafV600Eand c-Raf with IC50 values of 3.2, 0.8, and 5.0 nM, respectively.
• CASNO：1195768-06-9
• 分子式：C24H24F3N5O5S3
• 分子量：615.67
• SMILES：CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)O
• 保持条件：at -20°C 3 years Powder
• 同名：GSK-2118436 Mesylate, GSK2118436 Mesylate, GSK 2118436 Mesylate, GSK 2118436B
• 纯度：>98%
• 应用：Raf inhibitor
• 作用机制：Inhibitor