- 名称:Regorafenib monohydrate
- 简介:Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.
- CASNO:1019206-88-2
- 分子式:C21H17ClF4N4O4
- 分子量:500.83
- SMILES:CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O
- 保持条件:at -20°C 3 years Powder
- 同名:BAY 73-4506 monohydrate
- 纯度:>98%
- 应用:Tyrosine kinase inhibitor
- 作用机制:Inhibitor