- 名称:PLX7904
- 简介:PLX7904 is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.
- CASNO:1393465-84-3
- 分子式:C24H22F2N6O3S
- 分子量:512.53
- SMILES:O=C(C1=CNC2=NC=C(C3=CN=C(C4CC4)N=C3)C=C21)C5=C(F)C=CC(NS(=O)(N(CC)C)=O)=C5F
- 保持条件:at -20°C 3 years Powder
- 同名:PB04
- 纯度:>98%
- 应用:Raf inhibitor
- 作用机制:Inhibitor