• 名称：LY3023414
• 简介：LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and DNA-PK, extracted from patent WO/2012097039A1, compound example 1, has an IC50 of 64.9 nM, 42.1 nM, 10.6 nM, 19.1 nM for Akt1(pT308), Akt1 (pS473), P70S6(pT389), S6RP(pS240/242).
• CASNO：1386874-06-1
• 分子式：C23H26N4O3
• 分子量：406.49
• SMILES：CC(CN1C2=C3C=C(C=CC3=NC=C2N(C1=O)C)C4=CC(=CN=C4)C(C)(C)O)OC
• 保持条件：at -20°C 3 years Powder
• 同名：LY-3023414, LY 3023414
• 纯度：>98%
• 应用：PI3K/mTOR Dual Inhibitor
• 作用机制：Inhibitor