- 名称:ON 146040
- 简介:ON 146040 is the first dual PI3K and BCR-ABL inhibitor that targets the STAT3 and STAT5 pathways; inhibits PI3K α/δ isoforms with IC50 of 14/20 nM.
- CASNO:1404231-34-0
- 分子式:C24H23N7O3S
- 分子量:489.55
- SMILES:O=C(NC(C=NC(NC1=CC=C(N2CCN(C)CC2)C=C1)=N3)=C3S/4)C4=CC5=CC=C([N+]([O-])=O)C=C5
- 保持条件:at -20°C 3 years Powder
- 同名:ON-146040, ON146040
- 纯度:>98%
- 应用:dual PI3K and BCR-ABL inhibitor
- 作用机制:Inhibitor