- 名称:AZD1390
- 简介:AZD1390 is a first-in-class orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases.
- CASNO:2089288-03-7
- 分子式:C27H32FN5O2
- 分子量:477.57
- SMILES:O=C(N1C(C)C)N(C)C2=C1C3=CC(C4=CC=C(OCCCN5CCCCC5)N=C4)=C(F)C=C3N=C2
- 保持条件:at -20°C 3 years Powder
- 同名:AZD-1390, AZD 1390
- 纯度:>98%
- 应用:ATM inhibitor
- 作用机制:Inhibitor