• 名称：RAF709
• 简介：RAF709 is a potent inhibitor of B/C RAF kinase with almost equivalent IC50 values of 0.4 nM for B-RAF and C-RAF, showing a high level of selectivity, demonstrating greater than 99% on-target binding to BRAF, BRAFV600E, and CRAF at 1 μM and very few off-targets with DDR1 (>99%), DDR2 (86%), FRK (92%), and PDGFRb (96%), the only kinases with binding >80% at 1 μM.
• CASNO：1628838-42-5
• 分子式：C28H29F3N4O4
• 分子量：542.55
• SMILES：O=C(NC1=CN=C(C)C(C2=CC(N3CCOCC3)=C(OC4CCOCC4)N=C2)=C1)C5=CC(C(F)(F)F)=CC=C5
• 保持条件：at -20°C 3 years Powder
• 同名：RAF 709, RAF-709
• 纯度：>98%
• 应用：raf kinase inhibitor
• 作用机制：Inhibitor