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人RNF20(NM_019592)ORF克隆
人RNF20(NM_019592)ORF克隆
  • 商品货号:FO124882
  • 已售 3 件 | 评价 0 人次 | 关注度 293
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    • accession:NM_019592
    • 基因别名:RNF20
    • 基因描述:Homo sapiens ring finger protein 20, E3 ubiquitin protein ligase (RNF20), mRNA.
    • 载体: 现货载体
    • CDS区长度:2928
    • 翻译后氨基酸长度:975
    • 基因简介:The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列