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- 商品货号：G100868
- accession：NM_152410
- 基因别名：PACRG
- 基因描述：Homo sapiens PARK2 co-regulated (PACRG), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：891
- 翻译后氨基酸长度：296
- TranscriptVariant：This variant (1) represents the longest transcript and encodes the longer isoform (1).
- 基因简介：This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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