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- 商品货号：G101032
- accession：NM_133278
- 基因别名：FCAR
- 基因描述：Homo sapiens Fc fragment of IgA, receptor for (FCAR), transcript variant 8, mRNA.
- 载体：现货载体
- CDS区长度：762
- 翻译后氨基酸长度：253
- TranscriptVariant：This variant (8), also called deltaS2S366EC2 and CD89deltaS266EC2, lacks exon S2 and the last 66 nt of exon EC2 as compared to variant 1. As a result, variant 8 encodes isoform h, which has the same N- and C-termini but which lacks regions of 12 and 22 aa as compared to isoform a encoded by variant 1.
- 基因简介：This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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