- 商品货号:G101033
- accession:NM_133279
- 基因别名:FCAR
- 基因描述:Homo sapiens Fc fragment of IgA, receptor for (FCAR), transcript variant 9, mRNA.
- 载体:现货载体
- CDS区长度:720
- 翻译后氨基酸长度:239
- TranscriptVariant:This variant (9), also called alpha receptor b, lacks exon TM/C but contains 783 nt of sequence after exon EC2 that is present in the intron between exons EC2 and TM/C of variant 1. As a result, variant 9 encodes isoform i, which has the same N-terminus but a different C-terminus than isoform a encoded by variant 1.
- 基因简介:This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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