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人ACE2(NM_021804)ORF克隆 CALU-3细胞 vero E6非洲绿猴肾细胞
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MAPK 信号通路
Raf MEK p38-MAPK JNK/c-Jun ERK MNK TOPK AP-1 KLF
PI3K / Akt / mTOR 信号通路
Akt AMPK PI3K mTOR GSK-3 ATM / ATR PDK1 RSK DNA-PK
Cell Cycle | 细胞周期
Aurora Kinase CDK Chk PLK ROCK Ras c-Myc DYRK G-quadruplex
Protein Tyrosine Kinases
EGFR/HER2 PDGFR FLT3 c-MET FGFR VEGFR Src IGF-1R ALK Tie-2 ITK IRAK Ephrin Receptor Trk Receptors Tyrosine kinase TAM Receptor c-Kit CSF-1R
GPCR / G Protein | G蛋白偶联受体 / G蛋白
Metabotropic glutamate receptors (mGluR) 5-HT Receptors Adenosine Receptors Adrenergic Receptors Dopamine Receptors Histamine Receptors Platelet-Activating Factor (PAF) Receptors LPA Receptor Smoothened Receptors Opioid Receptors Melatonin Receptors CXCR Endothelin Receptors Neurokinin Receptors Cannabinoid Receptors G Protein CGRP Receptor Calcium-Sensing Receptor Prostanoid Receptors Glucagon Receptor Guanylate Cyclase Imidazoline Receptor CCK Neurotensin Receptors Peptide Receptors GHSR Sigma receptor Orexin Receptors S1P Receptor Oxytocin Receptor Bombesin Receptors Protease-Activated Receptors (PAR) Somatostatin Receptors GLP-1 receptors cAMP Vasopressin Receptor
Endocrinology/Hormones | 内分泌/荷尔蒙
Androgen Receptors Aromatase renin-angiotensin-aldosterone system (RAAS) Estrogen Receptors Glucocorticoid receptors 5-alpha-reductase Progesterone Receptors Vitamin D Receptors Pregnane X Receptors GPR GnRH receptor ROR
Cell Metabolism | 细胞代谢
HSP Cytochrome P450 DHFR PDE Dehydrogenases Factor Xa Antimetabolite Phospholipases Lipase Carbonic Anhydrase PPAR MAO Hydroxylases FAAH CETP LXR Retinoid Receptor Vitamin DGAT Lipid Metabolism Farnesyl Transferase Neuronal Metabolism NAMPT Glucokinase Ferroptosis Lactate dehydrogenase A (LDHA) Lipoxygenase HMG-CoA Reductase Fatty acid synthase (FASN) CRM1 Ribonucleotide Reductase IDO AhR Foxo1 GLUT FXR SREBP Thioredoxin Decarboxylase Oxidative Phosphorylation
Angiogenesis | 血管生成
HIF Bcr-Abl EGFR / HER2 VDA Syk BTK FAK
Others | 其他通路
Other inhibitors ACAT Phosphatase β-lactamase Cholinesterases Adenylyl Cyclase IDH1 PTEN Aldose Reductase Reagents DAPK gp120/CD4 Peptides NFAT PKG
Cytoskeleton | 细胞骨架
Microtubules Kinesin Mps1 Gap Junction Protein Integrin PAK Dynamin
Epigenetics | 表观遗传学
PARP DNA Methyltransferases Histone Methyltransferase Histone Demethylases Histone Acetyltransferases Epigenetic Reader Domain Protein Arginine Methyltransferases Protein serine/threonine phosphatase Protein Tyrosine Phosphatase
Apoptosis | 凋亡
Bcl-2 Family p53 TNF-α MDM2 Caspase IAP Protein kinase D (PKD) PERK Apoptosis Inducers Survivin ASK RIP Kinase
DNA Damage | DNA 损伤
Topoisomerase DNA, RNA Synthesis Synthetases HDAC Telomerase Sirtuins Synthases / Synthetases RNA/DNA Polymerase DNA alkylator IRE1 MTH1 DNA Stain
Immunology & Inflammation | 免疫及炎症
COX CCR LTR IL Receptor Toll-like Receptors NOS MALT ROS Keap1-Nrf2 Immunology & Inflammation related PD-1/PD-L1
Microbiology | 微生物学
Reverse Transcriptase Integrase Antifection
Membrane Transporters | 跨膜输运
Ion Channels/
NF-kB/IkB 信号通路
NF-κB IKK/IκB
JAK / Stat 信号通路
Stat JAK Pim
Proteases | 蛋白酶
HIV Protease Thrombin γ-Secretase HCV Protease Proteasome Aminopeptidase MMP DPP-4 Serine Protease Cysteine protease Carboxypeptidases Elastases Glutaminase ADAMs Urokinase
Neuronal Signaling | 神经信号通路
GABA Receptors Purinergic (P2Y) Receptors β-Amyloid Beta-secretase (BACE) AChR P2X Receptor NMDA Receptors CaMK GlyT
TGF-β / Smad 信号通路
Protein Kinase C (PKC) TGF-β / Smad Inhibitors Protein Kinase A (PKA)
Stem Cells / Wnt 信号通路
Hedgehog Casein Kinase Wnt Smoothened β-catenin Hippo
Ubiquitin | 泛素
E3 ligase E2 conjugating DUB E1 activating p97
Transferases | 转移酶
Phosphorylases Acyltransferases
Autophagy Signaling | 自噬
LRRK2 Autophagy
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